Does the Genetic Code Have A Eukaryotic Origin?

Does the Genetic Code Have A Eukaryotic Origin?

In the RNA world, RNA is assumed to be the dominant macromolecule performing most, if not all, core "house-keeping" functions. The ribo-cell hypothesis suggests that the genetic code and the translation machinery may both be born of the RNA world, and the introduction of DNA to ribo-cells may take over the informational role of RNA gradually, such as a mature set of genetic code and mechanism e...

Does the Modern Code Inspection Have Value?

For years, it was believed that the value of inspections is in nding and xing defects early in the development process. Otherwise, the cost to nd and x them later is much higher. However, in examining code inspection data, we are nding that inspections are bene cial for an additional reason. They make the code easier to understand and change. An analysis of data from a recent code inspection ex...

The origin of the genetic code.

A new approach to the origin of the genetic code is proposed based on some regularities in the nucleotide distribution pattern of the code. The relative amounts of various amino acids in primitive proteins were possibly different from those in organisms living today. The primordial ratio was supposed to shift to the modern one guided by the action of primitive nucleotides. Each primitive tRNA h...

Origin of the Genetic Code and Genetic Disorder

A Supersymmetric Model for the Evolution of the Genetic Code Abbreviation Footnote: Eukaryotic Code (ec), Vertebrate Mitochondrial Code (vmc)

A model is presented for the structure and evolution of the eukaryotic and vertebrate mitochondrial genetic codes, based on the representation theory of the Lie superalgebra A(5; 0) ' sl(6=1). A key role is played by pyrimidine and purine exchange symmetries in codon quartets.